Publications
Up one levelTitle: | A quantitative comparison of different methods to detect cardiorespiratory coordination during night-time sleep |
Type: | Article |
Authors/Creators: |
Cysarz D,
Bettermann H,
Lange S,
Geue D &
Van Leeuwen P
|
Source: |
Biomed Eng Online 2004, 3(1): 44
|
Description: |
Background: The univariate approaches used to analyze heart rate variability have recently been
extended by several bivariate approaches with respect to cardiorespiratory coordination. Some
approaches are explicitly based on mathematical models which investigate the synchronization
between weakly coupled complex systems. Others use an heuristic approach, i.e. characteristic
features of both time series, to develop appropriate bivariate methods.
Objective: In this study six different methods used to analyze cardiorespiratory coordination have
been quantitatively compared with respect to their performance (no. of sequences with
cardiorespiratory coordination, no. of heart beats coordinated with respiration). Five of these
approaches have been suggested in the recent literature whereas one method originates from
older studies.
Results: The methods were applied to the simultaneous recordings of an electrocardiogram and
a respiratory trace of 20 healthy subjects during night-time sleep from 0:00 to 6:00. The best
temporal resolution and the highest number of coordinated heart beats were obtained with the
analysis of 'Phase Recurrences'. Apart from the oldest method, all methods showed similar
qualitative results although the quantities varied between the different approaches. In contrast, the
oldest method detected considerably fewer coordinated heart beats since it only used part of the
maximum amount of information available in each recording.
Conclusions: The method of 'Phase Recurrences' should be the method of choice for the
detection of cardiorespiratory coordination since it offers the best temporal resolution and the
highest number of coordinated sequences and heart beats. Excluding the oldest method, the results
of the heuristic approaches may also be interpreted in terms of the mathematical models.
|
URL: | http://www.biomedical-engineering-online.com/content/3/1/44 |
Year: |
2004
|
Title: | Oscillations of heart rate and respiration synchronize during poetry recitation |
Type: | Article |
Authors/Creators: |
Cysarz D,
Von Bonin D,
Lackner H,
Heusser P,
Moser M &
Bettermann H
|
Source: |
Am J Physiol Heart Circ Physiol 2004, 287: H579-H587
|
Description: |
The objective
of this study was to investigate the synchronization between
low-frequency breathing patterns and respiratory sinus arrhythmia
(RSA) of heart rate during guided recitation of poetry, i.e., recitation
of hexameter verse from ancient Greek literature performed in a
therapeutic setting. Twenty healthy volunteers performed three different
types of exercises with respect to a cross-sectional comparison:
1) recitation of hexameter verse, 2) controlled breathing, and 3)
spontaneous breathing. Each exercise was divided into three successive
measurements: a 15-min baseline measurement (S1), 20 min of
exercise, and a 15-min effect measurement (S2). Breathing patterns
and RSA were derived from respiratory traces and electrocardiograms,
respectively, which were recorded simultaneously using an
ambulatory device. The synchronization was then quantified by the
index, which has been adopted from the analysis of weakly coupled
chaotic oscillators. During recitation of hexameter verse, was high,
indicating prominent cardiorespiratory synchronization. The controlled
breathing exercise showed cardiorespiratory synchronization
to a lesser extent and all resting periods (S1 and S2) had even fewer
cardiorespiratory synchronization. During spontaneous breathing, cardiorespiratory
synchronization was minimal and hardly observable.
The results were largely determined by the extent of a low-frequency
component in the breathing oscillations that emerged from the design
of hexameter recitation. In conclusion, recitation of hexameter verse
exerts a strong influence on RSA by a prominent low-frequency
component in the breathing pattern, generating a strong cardiorespiratory
synchronization.
|
Year: |
2004
|
Title: | Is there evidence of fetal-maternal heart rate synchronization? |
Type: | Article |
Authors/Creators: |
Van Leeuwen P,
Geue D,
Lange S,
Cysarz D,
Bettermann H &
Grönemeyer D
|
Source: |
BMC Physiol 2003, 3: 2
|
Description: |
Background: The prenatal condition offers a unique possibility of examining physiological
interaction between individuals. Goal of this work was to look for evidence of coordination
between fetal and maternal cardiac systems.
Methods: 177 magnetocardiograms were recorded in 62 pregnancies (16th–42nd week of
gestation). Fetal and maternal RR interval time series were constructed and the phases, i.e. the
timing of the R peaks of one time series in relation to each RR interval of the other were
determined. The distributions of these phases were examined and synchrograms were constructed
for real and surrogate pairs of fetal and maternal data sets. Synchronization epochs were
determined for defined n:m coupling ratios.
Results: Differences between real and surrogate data could not be found with respect to number
of synchronization epochs found (712 vs. 741), gestational age, subject, recording or n:m
combination. There was however a preference for the occurrence of synchronization epochs in
specific phases in real data not apparent in the surrogate for some n:m combinations.
Conclusion: The results suggest that occasional coupling between fetal and maternal cardiac
systems does occur
|
URL: | http://www.biomedcentral.com/content/pdf/1472-6793-3-2.pdf |
Year: |
2003
|
Title: | Effects of speech therapy with poetry on heart rate rhythmicity and cardiorespiratory coordination |
Type: | Article |
Authors/Creators: |
Bettermann H,
Von Bonin D,
Frühwirth M,
Cysarz D &
Moser M
|
Source: |
Int J Cardiol 2002, 84(1): 77-88
|
Description: |
Our objective was to study the effects of guided rhythmic speech with poetry,
referred to as Anthroposophical Therapeutic Speech (ATS), on binary differential
heart rate dynamics (also called musical heart rate rhythmicity or HRR) as well as
on classical spectral parameters during the 15 minutes after speech exercise has
ended. A total of 105 one-hour sessions with speech or control exercises were
performed in 7 healthy subjects, with 15 sessions each. Heart rate was recorded
with ambulatory solid state recorders. Sessions were divided into 15 minutes baseline
measurement (S1), 30 mi nutes of exercise, and 15 minutes effect measurement
(S2). The overall binary pattern predominance (PP) as well as the frequency
of predominant and cyclically recurrent cardiorespiratory phase locking patterns
were calculated from HRR and their changes from S1 to S2 were compared with
the changes in low and high frequency heart rate variability. The results showed
that: (1) ATS provokes alterations in heart rate dynamics which are different from
those after control exercises and which persist at least for 15 minutes following
exercise; (2) in comparison to spectral parameters of heart rate variability, pattern
predominance discloses the effects of rhythmic speech exercises best; and (3) cardiorespiratory
phase locking patterns, which contribute most to the rhythm pattern
predominance, are more prominent after ATS.
|
File: | Download here (95 kBytes) |
Year: |
2002
|
Title: | Comparison of two different approaches in the detection of intermittent cardiorespiratory coordination during night sleep |
Type: | Article |
Authors/Creators: |
Bettermann H,
Cysarz D &
Van Leeuwen P
|
Source: |
BMC Physiol 2002, 2: 18
|
Description: |
Background: The objective was to evaluate and to compare two completely different detection
algorithms of intermittent (short-term) cardiorespiratory coordination during night sleep. The first
method is based on a combination of respiratory flow and electrocardiogram recordings and
determines the relative phases of R waves between successive onsets of inspiration. Intermittent
phase coordination is defined as phase recurrence with accuracy α over at least k heartbeats. The
second, recently introduced method utilizes only binary coded variations of heart rate (acceleration
= 1, deceleration = 0) and identifies binary pattern classes which can be assigned to respiratory
sinus arrhythmia (RSA). It is hypothesized that RSA pattern class recurrence over at least k
heartbeats is strongly related with the intermittent phase coordination defined above.
Results: Both methods were applied to night time recordings of 20 healthy subjects. In subjects
<45 yrs and setting k = 3 and α = 0.03, the phase and RSA pattern recurrence were highly
correlated. Furthermore, in most subjects the pattern predominance (PP) showed a pronounced
oscillation which is most likely linked with the dynamics of sleep stages. However, the analysis of
bivariate variation and the use of surrogate data suggest that short-term phase coordination mainly
resulted from central adjustment of heart rate and respiratory rate rather than from real phase
synchronization due to physiological interaction.
Conclusion: Binary pattern analysis provides essential information on short-term phase
recurrence and reflects nighttime sleep architecture, but is only weakly linked with true phase
synchronization which is rare in physiological processes of man.
|
File: | Download here (1172 kBytes) |
URL: | http://www.biomedcentral.com/content/pdf/1472-6793-2-18.pdf |
Year: |
2002
|
Title: | Heart rate dynamics and cardiorespiratory coordination in diabetic and breast cancer patients |
Type: | Article |
Authors/Creators: |
Bettermann H,
Kröz M,
Girke M &
Heckmann C
|
Source: |
Clin Physiol 2001, 21(4): 411-420
|
Description: |
Objective of this study was to evaluate cardiac autonomic function in female breast cancer
patients on the basis of linear and nonlinear heart rate variability (HRV) as well as
on musical heart rate rhythmicity. The latter method has been recently developed and
enables particularly the quantification of cardiorespiratory coordination solely on the
basis of ECG recordings. To provide a broad basis of comparability, 37 breast cancer
patients were compared with 37 age-matched healthy women and 40 age-matched female
diabetic patients who serve as pathological controls. During night sleep, all parameters
showed a tendency towards lower variability, complexity, or rhythmicity of
HRV in cancer patients. The most prominent alterations were found for the binary pattern
predominance and for the ratio of heart rate and respiration. In particular, when
comparing metastasized and non-metastasized cancer patients, the discriminatory power
of binary heart rate rhythmicity emerges: the histograms of one-hour intervals during
night sleep with a predominance of cyclically recurrent phase locking patterns unveiled
a clear transition from higher to lower cardiorespiratory coordination ratios and to a loss
of coordination capability in metastasized patients.
|
File: | Download here (77 kBytes) |
Year: |
2001
|
Title: | Effects of an anthroposophical remedy on cardiorespiratory regulation |
Type: | Article |
Authors/Creators: |
Cysarz D,
Heckmann C,
Bettermann H &
Kümmell HC
|
Source: |
Altern Ther Health Med 2002, 8: 78-83
|
Year: |
2002
|
Title: | Bimodal dose-dependent effect on autonomic cardiac control after oral administration of Atropa belladonna |
Type: | Article |
Authors/Creators: |
Bettermann H,
Cysarz D,
Portsteffen A &
Kümmell HC
|
Source: |
Auton Neurosci (J Auton Nerv Syst) 2001, 90: 132-137
|
Description: |
This single-blind placebo controlled study was designed to investigate the dose-dependent
vagolytic and vagotonic effects after a single oral administration of Atropa belladonna tincture
(ABT, 0.1 mg/ml alkaloid concentration, atropine:scopolamine = 20:1). In 8 healthy
young subjects, heart rate and noninvasive arterial finger blood pressure were recorded simultaneously
over 4 h after oral application of 4 different doses of ABT (day 1: 2 ml, day 2: placebo,
day 3: 5 ml, day 4: 1 ml). On each day, 14 20-min sequences under controlled experimental
conditions were performed. Among others, mean RR interval (RR), high frequency
spectral power of heart rate variability (HF), and noninvasive baroreflex sensitivity (BRS)
were calculated during metronome breathing in supine position. These parameters were robust
markers of vagal activity. One hour after 5ml ABT, RR, HF and BRS decreased clearly in 6
of 8 subjects. This effect was interpreted as vagolytic response. After 1 and 2ml ABT, and
after placebo, RR and HF increased markedly. The increase after ABT was much higher than
the increase solely due to adaptation after placebo administration, and it could be clearly identified
as an augmentation of vagal cardiac activity caused by low-dose ABT. In conclusion,
low doses of orally administered ABT can be effectively used to stimulate parasympathetic
activity in man. The mode of vagal activation changes between 2 and 5 ml ABT from vagotonic
to vagolytic. ABT has no or very little effect on blood pressure control.
|
File: | Download here (61 kBytes) |
Year: |
2001
|
Title: | Irregularities and nonlinearities in fetal heart period time series in the course of pregnancy |
Type: | Article |
Authors/Creators: |
Cysarz D,
Van Leeuwen P &
Bettermann H
|
Source: |
Herzschr Elektrophys 2000, 11: 179-183
|
Description: |
Fetal heart rate variability reflects fetal development and is
affected by pathological conditions. The aim of this study was to examine
fetal heart period irregularity by focussing on nonlinear dynamical components.
We recorded 165 fetal magnetocardiograms in 39 healthy pregnancies
between the 16th and 41st week. The irregularity of the RR time series of
each recording was quantified on the basis of the approximate entropy
(ApEn). In order to estimate the nonlinear component, a surrogate time series
was generated for each time series and ApEn was again calculated. Next, the
purely dynamical aspect of the series was examined using a binary representation
reflecting increase or decrease in RR interval of the original time series.
ApEn of the original time series increased during pregnancy with a significant
dependence on gestational age (p<0.0005). The ApEn values of the surrogate
data increased similarly although the power of the relationship to week of
gestation was weaker (roriginal=0.68, rsurrogate=0.46). Also the values of the
surrogate series were generally higher, the mean difference being 0.24±0.24
(p<0.0005). ApEn of the binary series revealed no dependency on gestational
age but again the values for the surrogate series were higher than those for the
original series. The increase in irregularity of RR interval time series during
pregnancy can be attributed in part to an irregular, nonlinear temporal structure
and is not solely due to linear autocorrelations. Reducing information by
constructing time series using binary symbolization which ignores the absolute
beat durations resulted in a loss of dependency on gestational age but
a retention of nonlinearity. The ability to quantify these processes promises
to aid in prenatal risk stratification.
|
File: | Download here (73 kBytes) |
Year: |
2000
|
Title: | The status of nonlinear dynamics in the analysis of heart rate variability (editorial) |
Type: | Editorial |
Authors/Creators: |
Van Leeuwen P &
Bettermann H
|
Source: |
Herzschr Elektrophys 2000, 11: 127-130
|
File: | Download here (38 kBytes) |
Year: |
2000
|
Title: | Heart rate variability: How to assess effects of mild therapies on autonomic control in small groups of mild and borderline hypertensives? |
Type: | Letter |
Authors/Creators: |
Bettermann H,
Cysarz D &
Kümmell HC
|
Source: |
Hypertension 2000, 35: e6-e7
|
Year: |
2000
|
Title: | Musikalischer Rhythmus im Herzschlag des Menschen |
Type: | Article |
Authors/Creators: |
Bettermann H
|
Source: |
Medizin Individuell 2000, 2: 17
|
Year: |
2000
|
Title: | Evaluation of modulations in heart rate variability caused by a composition of herbal extracts |
Type: | Article |
Authors/Creators: |
Cysarz D,
Schürholz T,
Bettermann H &
Kümmell HC
|
Source: |
Arzneimittelforschung / Drug Research 2000, 50: 420-424
|
Year: |
2000
|
Title: | Entropies of short binary sequences in heart period dynamics |
Type: | Article |
Authors/Creators: |
Cysarz D,
Bettermann H &
Van Leeuwen P
|
Source: |
Am J Physiol 2000, 278 (6) H2163-H2172
|
Description: |
Dynamical aspects of RR intervals have often been analyzed by means of linear and nonlinear
measures. The goal of this study was to analyze binary sequences, in which only the
dynamical information is retained, by means of two different aspects of regularity. RR
interval sequences derived from 24-hour ECG recordings of 118 healthy subjects were
converted to symbolic binary sequences which coded the beat-to-beat increase or decrease in
RR interval. Shannon entropy was used to quantify the occurrence of short binary patterns
(length N=5) in binary sequences derived from 10-minute intervals. The regularity of the
short binary patterns was analyzed on the basis of approximate entropy (ApEn). ApEn had a
linear dependence on mean RR interval length, increasing irregularity occurring at longer RR
interval length. Shannon entropy of the same sequences showed that the increase in
irregularity is accompanied by a decrease of occurrence of some patterns. Taken together, this
indicates that irregular binary patterns are more probable when the mean RR interval
increases. The use of surrogate data confirmed a nonlinear component in the binary sequence.
Analysis of two consecutive 24-hour ECG recordings for each subject demonstrated good
intraindividual reproducibility of the results. In conclusion, quantification of binary sequences
derived from ECG recordings reveals properties that cannot be found using the full
information of RR interval sequences.
|
File: | Download here (146 kBytes) |
Year: |
2000
|
Title: | Detecting cardiorespiratory coordination by respiratory pattern analysis of heart period dynamics -- the musical rhythm approach |
Type: | Article |
Authors/Creators: |
Bettermann H,
Cysarz D &
Van Leeuwen P
|
Source: |
Int J Bifurcation & Chaos 2000, 10(10), 2349-2360
|
Description: |
The purpose of this study was to demonstrate that cardiorespiratory coordination can be unveiled
by analyzing solely heart period data from the electrocardiogram (ECG). The analysis
was done (1) on the basis of symbolic musical pattern analysis to detect intermittent cardiorespiratory
phase coordination and (2) on the quantitative evaluation of respiratory sinus arrhythmia
(RSA) to examine long-term frequency coordination between heartbeat and respiration.
The methods were applied to 196 ECGs of 98 healthy subjects. The results showed that
at night (1) intermittent phase coordination occurred reproducibly in individual subjects, and
(2) long-term frequency ratios statistically approached 4:1 over all subjects to within an accuracy
of 0.02, although individual values ranged from 2.5 – 6.0 with a high intraindividual reproducibility
(r = 0.94, day A vs. day B). Moreover, intermittent phase coordination ratios
and long-term frequency ratios corresponded to each other with a remarkably high correlation
(r = 0.95). In the light of clinical applications, the coordination analysis presented here has an
enormous advantage over those techniques depending on respiratory flow measurements, because
the pattern technique requires only ECG recordings, and it is thus applicable over a
longer period of time under daily life conditions.
|
File: | Download here (108 kBytes) |
Year: |
2000
|
Title: | Presence of irregularity in fetal heart period time series |
Type: | Article |
Authors/Creators: |
Van Leeuwen P,
Cysarz D &
Bettermann H
|
Source: |
Med Biol Eng Comput 1999, 37 Suppl. 2: 440-441
|
Year: |
1999
|
Title: | Musical rhythms in heart period dynamics -- A cross-cultural and interdisciplinary approach to cardiac rhythms |
Type: | Article |
Authors/Creators: |
Bettermann H,
Amponsah D,
Cysarz D &
Van Leeuwen P
|
Source: |
Am J Physiol 1999, 277 (5): H1762-H1770
|
Description: |
The purpose of this study was to
expand classic heart period analysis methods by techniques
from ethnomusicology that explicitly take complex musical
rhythm principles into consideration. The methods used are
based on the theory of African music, the theory of symbolic
dynamics, and combinatorial theory. Heart period tachograms
from 192 24-h electrocardiograms of 96 healthy subjects
were transformed into binary symbol sequences that
were interpretable as elementary rhythmic (percussive) patterns,
the time lines in African music. Using a hierarchical
rhythm pattern scheme closely related to the Derler Rhythm
Classification (from jazz theory), we calculated the predominance
and stability of pattern classes. The results show that
during sleep certain classes, specific to individuals, occurred
in a cyclically recurrent manner and many times more often
than expected. Simultaneously, other classes disappeared
more or less completely. Moreover, the most frequent classes
obviously originate from phase-locking processes in autonomic
regulation (e.g., between respiratory and cardiac cycles).
In conclusion, the new interdisciplinary method presented
here demonstrates that heart period patterns, in particular
those occurring during night sleep, can be interpreted as
musical rhythms. This method may be of great potential use
in music therapy research.
|
File: | Download here (411 kBytes) |
URL: | http://ajpheart.physiology.org/cgi/content/abstract/277/5/H1762 |
Year: |
1999
|
Title: | Magnetocardiography in the determination of fetal heart rate complexity |
Type: | Article |
Authors/Creators: |
Van Leeuwen P,
Bettermann H,
Schüssler M &
Lange S
|
Publisher: |
NY: Springer
|
Source: |
In: Aine CJ, Okada Y, Stroink G, Swithenby SJ, Wood CC, eds. Biomag 96. Proceedings of the tenth international conference on Biomagnetism
|
Year: |
1999
|
Title: | Fetal heart rate variability and complexity in the course of pregnancy |
Type: | Article |
Authors/Creators: |
Van Leeuwen,
Lange S,
Bettermann H,
Grönemeyer D &
Hatzmann W
|
Source: |
Early Hum Dev 1999, 54: 259-269
|
Year: |
1999
|
Title: | Hypertonie und Rhythmisches System: Erste Ergebnisse der Beobachtungsstudie |
Type: | Article |
Authors/Creators: |
Bettermann H &
Kümmell HC
|
Publisher: |
Bern: Peter Lang
|
Source: |
In: Heusser P. (Hrsg.) Akademische Forschung in der Anthroposophischen Medizin. pp203-206
|
Year: |
1999
|
Title: | Zum Tagesgang der Atemfrequenz |
Type: | Article |
Authors/Creators: |
Heckmann C,
Engelke P,
Cysarz D,
Bettermann H &
Kümmell HC
|
Publisher: |
Bern: Peter Lang
|
Source: |
In: Heusser P. (Hrsg.) Akademische Forschung in der Anthroposophischen Medizin. pp139-147
|
Year: |
1999
|
Title: | Evidence of phase transitions in heart period dynamics |
Type: | Article |
Authors/Creators: |
Bettermann H &
Van Leeuwen P
|
Source: |
Biol Cybern 1998, 78: 63-70
|
Description: |
Complexity measures of non-linear dynamics are
a useful tool for quantifying observed stretching, folding,
scaling and mixing processes in the Takens-reconstructed
state space of heart period dynamics. Although such measures
are not suited to provide evidence of deterministic
chaos or to estimate true fractal dimensions and Lyapunov
spectra in heart period time series, they allow the classification
of RR dynamics and the identification of changes in
RR complexity (RRC). The aim of this study was to develop
appropriate measures and examine their utility in identifying
the physiological effect of changes between the sleeping
and waking state. Twenty-four hour electrocardiography
(ECG) recordings and diaries noting their waking/sleeping
period were obtained from 78 healthy subjects, aged 20 to 55
years. The approximate information dimension (ApD1) and
the approximate Kolmogorov entropy (ApEn), introduced
by Pincus, Kaplan and others, were modified in order to allow
the calculation of strictly local values. That is, the local
or pointwise dimensions and entropies were calculated for
each reference vector with respect to its symmetric neighbourhood
in time. For each subject the values for the local
measures were averaged for 10-min periods, resulting in 144
global values over 24 h. Similarly, low- and high-frequency
spectral parameters were calculated. All measures were examined
and compared for the waking and the sleeping periods.
All complexity measures as well as to a lesser degree
high-frequency power showed a linear dependency on
mean RR interval with a large individual variation. For the
RRC measures this linear correlation was separated into two
different clusters corresponding to the sleeping and waking
periods. In almost all cases the correlation was greater in the
waking period. In particular, in many cases no correlation
was observed in the sleeping period. However, the r values
for LF were appreciably lower and indicated solely a weak
relationship to the RR interval in the waking period. Analysis
of variance combining mean RR interval with RRC or
spectral parameters singly and in couples revealed that the
best separation with respect to physiological state could be
achieved with the complexity measures, in particular with
ApEn. The results show evidence of at least two dynamical
regimes (phases) of heart period dynamics and a close
but different functional relationship within the phases between
RR interval and RR complexity. The separation between
these regimes and the relatively sudden shift from one
regime to the other suggest the existence of a phase transition
with respect to waking and sleeping periods in terms of
synergetics.
|
File: | Download here (203 kBytes) |
Year: |
1998
|
Title: | Komplexitätsanalyse der fetalen Herzfrequenz -- Bestimmung der Dimension |
Type: | Article |
Authors/Creators: |
Lange S,
Van Leeuwen P,
Bettermann H &
Grönemeyer D
|
Source: |
Biomed Tech 1997, 42: (E1) 59-60
|
Year: |
1997
|
Title: | Gesteigerte LF-Herzperiodenvariabilität tagsüber nach 4-wöchiger Rehabilitation bei Patienten mit koronarer Herzkrankheit |
Type: | Article |
Authors/Creators: |
Bettermann H,
Karoff M,
Schulte M &
Kümmell HC
|
Source: |
Herz Kreislauf 1997, 29: 56-60
|
Year: |
1997
|
Title: | Die Bestimmung der Atemfrequenz aus der respiratorischen Sinusarrhythmie |
Type: | Article |
Authors/Creators: |
Bettermann H,
Engelke P,
Van Leeuwen P &
Heckmann C
|
Source: |
Biomed Tech 1996, 41 (11): 319-323
|
Description: |
In der klinischen Praxis ist die Beobachtung ungestörter Spontanatmung und die Messung
einer ‘unbeeinflußten’ Atemfrequenz praktisch unmöglich. Die über die respiratorische Sinusarrhythmie
(RSA) elektrokardiographisch ermittelte Atemfrequenz bietet eine praktikable
Alternative. In der vorliegenden Arbeit werden ein altes und ein neues Verfahren zur Atemfrequenzregistrierung
aus dem EKG vorgestellt und miteinander verglichen. Das ältere bisherige
Verfahren sucht ausgeprägte Maxima im atmungsrelevanten Bereich des Amplitudenspektrum
einer 5-minütigen Zeitreihe der Momentanherzperiode (RR-Zeitreihe). Das neue
Verfahren basiert auf einer Bandpassfilterung einer 1-minütigen RR-Zeitreihe und der anschließenden
Analyse der Maxima, Minima und Nulldurchgänge der so ermittelten RSAAtemkurve.
Zum Vergleich der Verfahren wurde die Atemfrequenz bei 16 männlichen Probanden
unter 15 verschiedenen Versuchssituationen mit und ohne Taktatmung sowohl elektrokardiographisch
als auch mit einem Atemthermistor direkt ermittelt. Die mittlere Abweichung
vom direkt gemessenen Atemfrequenzwert lag für das bisherige Verfahren im Mittel
bei 7,2 min-1, für das neue Verfahren bei 2,9 min-1. Nur bei Taktatmung 6 min-1 und Taktatmung
12 min-1 sitzend liefert das neue Verfahren ungenauere Atemfrequenzwerte. Die vorliegende
Studie demonstriert die hohe Genauigkeit der aus der RSA-Atemkurve ermittelten
mittleren Atemfrequenz. Das Verfahren erlaubt den Einsatz im klinischen Alltag und ermöglicht
eine einfach zu realisierende Langzeit-Atemfrequenzregistrierung.
|
File: | Download here (85 kBytes) |
Year: |
1996
|
Title: | Komplexitätsanalyse der RR-Dynamik im 24-Stunden-EKG -- Entwicklung, Visualisierung und Anwendung einer klinisch orientierten Chaosmetrie |
Type: | Dissertation |
Authors/Creators: |
Bettermann H
|
Publisher: |
Egelsbach: Hänsel Hohenhausen
|
Source: |
Deutsche Hochschulschriften Band 2316
|
Year: |
1996
|
Title: | Ergebnisse rhythmologischer Untersuchungen von Cardiodoron an Gesunden |
Type: | Article |
Authors/Creators: |
Kümmell HC &
Bettermann H
|
Source: |
Merkurstab 1996, 5: 361-371
|
Year: |
1996
|
Title: | Circadian aspects of apparent correlation dimension in human heart rate dynamics |
Type: | Article |
Authors/Creators: |
Van Leeuwen P,
Bettermann H,
An der Heiden U &
Kümmell HC
|
Source: |
Am J Physiol 1995, 269: H130-H134
|
Year: |
1995
|
Title: | Magnetokardiographie zur Erfassung fetaler Herzaktionen |
Type: | Article |
Authors/Creators: |
Van Leeuwen P,
Schüssler M,
Bettermann H,
Lange S &
Hatzmann W
|
Source: |
Geburtshilfe, Frauenheilkunde 1995, 55
|
Year: |
1995
|
Title: | Magnetokardiographie zur Erfassung fetaler Herzaktionen |
Type: | Abstract |
Authors/Creators: |
Van Leeuwen P,
Schüssler M &
Bettermann H
|
Source: |
Abstract in Z Kardiol 1994, 83 (9): 698
|
Year: |
1994
|
Title: | Dimensional analysis of RR dynamic in 24 hour electrocardiograms |
Type: | Article |
Authors/Creators: |
Bettermann H &
Van Leeuwen P
|
Source: |
Acta Biotheor 1992, 40 (4): 297-312
|
Year: |
1992
|
Created
2005
by user
admin
Time of request 23/08/2019 11:12 (GMT+2)
© Copyright 2005 Scientific African
Time of request 23/08/2019 11:12 (GMT+2)
© Copyright 2005 Scientific African